1ANC

ANIONIC TRYPSIN MUTANT WITH SER 214 REPLACED BY LYS

Summary for 1ANC

Entry DOI	10.2210/pdb1anc/pdb
Descriptor	ANIONIC TRYPSIN, CALCIUM ION, BENZAMIDINE, ... (4 entities in total)
Functional Keywords	trypsin, anionic, serine protease, hydrolase
Biological source	Rattus rattus (black rat)
Cellular location	Secreted, extracellular space: P00763
Total number of polymer chains	1
Total formula weight	24137.32
Authors	Fletterick, R.J.,Mcgrath, M.E. (deposition date: 1994-12-21, release date: 1997-04-01, Last modification date: 2021-11-03)
Primary citation	McGrath, M.E.,Vasquez, J.R.,Craik, C.S.,Yang, A.S.,Honig, B.,Fletterick, R.J. Perturbing the polar environment of Asp102 in trypsin: consequences of replacing conserved Ser214. Biochemistry, 31:3059-3064, 1992 Cited by PubMed: 1554694 DOI: 10.1021/bi00127a005 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation