8HGE

Crystal structure of the CYP153A mutant V456A from Marinobacter aquaeolei in complex with 12-hydroxydodecanoic acid

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	B	Cytochrome P450	polymer	480	55251.0	1	UniProt (A0A368UNN3) Pfam (PF00067) In PDB	Marinobacter nauticus
2	B	PROTOPORPHYRIN IX CONTAINING FE	non-polymer		616.5	1	Chemie (HEM)
3	B	12-HYDROXYDODECANOIC ACID	non-polymer		216.3	1	Chemie (12H)
4		water	water		18.0	549	Chemie (HOH)

Sequence modifications

B: 5 - 474 (UniProt: A0A368UNN3)

PDB	External Database	Details
Met 3	-	initiating methionine
Gly 4	-	expression tag
Ala 460	Val 456	engineered mutation
Leu 475	-	expression tag
Glu 476	-	expression tag
His 477	-	expression tag
His 478	-	expression tag
His 479	-	expression tag
His 480	-	expression tag
His 481	-	expression tag
His 482	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	55251.0
Non-Polymers*	Number of molecules	2
	Total formula weight	832.8
All*	Total formula weight	56083.8

*Water molecules are not included.