8H0N
Crystal structure of the human METTL1-WDR4 complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4 | polymer | 367 | 40359.6 | 1 | UniProt (P57081) Pfam (PF00400) In PDB | Homo sapiens (human) | Protein Wuho homolog,hWH,WD repeat-containing protein 4 |
| 2 | B | tRNA (guanine-N(7)-)-methyltransferase | polymer | 244 | 28219.3 | 1 | UniProt (Q9UBP6) Pfam (PF02390) In PDB | Homo sapiens (human) | Methyltransferase-like protein 1,mRNA (guanine-N(7)-)-methyltransferase,miRNA (guanine-N(7)-)-methyltransferase,tRNA (guanine(46)-N(7))-methyltransferase,tRNA(m7G46)-methyltransferase |
| 3 | water | water | 18.0 | 500 | Chemie (HOH) |
Sequence modifications
B: 0 - 236 (UniProt: Q9UBP6)
| PDB | External Database | Details |
|---|---|---|
| Ser 107 | Cys 136 | conflict |
| Ser 179 | Cys 208 | conflict |
| Leu 237 | - | expression tag |
| Glu 238 | - | expression tag |
| His 239 | - | expression tag |
| His 240 | - | expression tag |
| His 241 | - | expression tag |
| His 242 | - | expression tag |
| His 243 | - | expression tag |
| His 244 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 68578.9 | |
| All* | Total formula weight | 68578.9 |
