8GLL

R149E variant of Citrate Synthase (CitA) in Mycobacterium tuberculosis

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E...	citrate synthase	polymer	379	40991.5	8	UniProt (A0A045JB88) Pfam (PF00285) UniProt (by SIFTS) (P9WPD3) In PDB	Mycobacterium tuberculosis H37Rv
2	B, E, H, D, C...	1,2-ETHANEDIOL	non-polymer		62.1	75	Chemie (EDO)
3	D, C, A, E, H...	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	11	Chemie (PEG)
4	B, E, H, F, G...	SULFATE ION	non-polymer		96.1	15	Chemie (SO4)
5		water	water		18.0	581	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F, G, H: 1 - 373 (UniProt: A0A045JB88)

PDB	External Database	Details
Glu 149	Arg 149	engineered mutation
His 374	-	expression tag
His 375	-	expression tag
His 376	-	expression tag
His 377	-	expression tag
His 378	-	expression tag
His 379	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	327932.2
Non-Polymers*	Number of molecules	101
	Total formula weight	7263.4
All*	Total formula weight	335195.5

*Water molecules are not included.