8FX3

Crystal structure of the Trypanosoma cruzi hypoxanthine-guanine-xanthine phosphoribosyltransferase (HGXPRT), isoform D, bound to Immucillin-GP, showing the structure of the complete active site in its open conformation

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Hypoxanthine-guanine phosphoribosyltransferase	polymer	231	25883.0	2	UniProt (A0A7J6XZA2) Pfam (PF00156) UniProt (by SIFTS) (Q4DGA2) In PDB	Trypanosoma cruzi (strain CL Brener)
2	A, B	PHOSPHORIC ACID MONO-[5-(2-AMINO-4-OXO-4,5-DIHYDRO-3H-PYRROLO[3,2-D]PYRIMIDIN-7-YL)-3,4-DIHYDROXY-PYRROLIDIN-2-YLMETHYL] ESTER	non-polymer		361.2	2	Chemie (IMU)
3		water	water		18.0	308	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	51766.0
Non-Polymers*	Number of molecules	2
	Total formula weight	722.5
All*	Total formula weight	52488.5

*Water molecules are not included.