8EM4

Cryo-EM structure of LRP2 at pH 7.5

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Low-density lipoprotein receptor-related protein 2	polymer	4660	519746.5	2	UniProt (A2ARV4) Pfam (PF00057) Pfam (PF00058) Pfam (PF14670) Pfam (PF07645) Pfam (PF12662) In PDB	Mus musculus (house mouse)	LRP-2,Glycoprotein 330,gp330,Megalin
2	C, D	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	2	In PDB GlyTouCan (G42666HT)
3	B, A	2-acetamido-2-deoxy-beta-D-galactopyranose	non-polymer		221.2	32	Chemie (NGA)
4	A, B	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	58	Chemie (NAG)
5	A, B	CALCIUM ION	non-polymer		40.1	84	Chemie (CA)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	1039493.0
Branched	Number of molecules	2
	Total formula weight	848.8
Non-Polymers*	Number of molecules	174
	Total formula weight	23275.3
All*	Total formula weight	1063617.1

*Water molecules are not included.