8DFE

Crystal Structure of SARS-CoV-2 Main Protease (Mpro) S144L Mutant

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	3C-like proteinase nsp5	polymer	306	33851.6	1	UniProt (P0DTD1) Pfam (PF05409) In PDB	Severe acute respiratory syndrome coronavirus 2	3CL-PRO,3CLp,Main protease,Mpro,Non-structural protein 5,nsp5,SARS coronavirus main proteinase
2		water	water		18.0	201	Chemie (HOH)

Sequence modifications

A: 1 - 306 (UniProt: P0DTD1)

PDB	External Database	Details
Leu 144	Ser 3407	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	33851.6
All*	Total formula weight	33851.6

*Water molecules are not included.