8CQB

Cryo-EM structure of the human GBP1 dimer bound to GDP-AlF3

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Guanylate-binding protein 1	polymer	592	68021.6	2	UniProt (P32455) Pfam (PF02263) Pfam (PF02841) In PDB	Homo sapiens (human)	GTP-binding protein 1,GBP-1,HuGBP-1,Guanine nucleotide-binding protein 1,Interferon-induced guanylate-binding protein 1
2	A, B	GUANOSINE-5'-DIPHOSPHATE	non-polymer		443.2	2	Chemie (GDP)
3	A, B	ALUMINUM FLUORIDE	non-polymer		84.0	2	Chemie (AF3)
4	A, B	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	136043.2
Non-Polymers*	Number of molecules	6
	Total formula weight	1103.0
All*	Total formula weight	137146.2

*Water molecules are not included.