8AYY

Poliovirus type 3 (strain Saukett) stabilised virus-like particle (PV3 SC8) in complex with GSH and Pleconaril

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Capsid protein, VP1	polymer	300	33562.8	1	UniProt (Q84895) Pfam (PF00073) In PDB	Human poliovirus 3
2	B	Capsid protein, VP0	polymer	340	37623.0	1	UniProt (Q84895) Pfam (PF02226) Pfam (PF00073) In PDB	Human poliovirus 3
3	C	Capsid protein, VP3	polymer	238	26315.1	1	UniProt (Q84895) Pfam (PF00073) In PDB	Human poliovirus 3
4	A	3-{3,5-DIMETHYL-4-[3-(3-METHYL-ISOXAZOL-5-YL)-PROPOXY]-PHENYL}-5-TRIFLUOROMETHYL-[1,2,4]OXADIAZOLE	non-polymer		381.3	1	Chemie (W11)
5	C	GLUTATHIONE	non-polymer		307.3	1	Chemie (GSH)

Sequence modifications

A: 1 - 300 (UniProt: Q84895)

PDB	External Database	Details
Met 105	Thr 683	engineered mutation
Leu 132	Phe 710	engineered mutation

B: 1 - 340 (UniProt: Q84895)

PDB	External Database	Details
Ala 67	Unk 67	engineered mutation
Ile 87	Leu 87	engineered mutation
Met 284	Leu 284	engineered mutation
Glu 310	Asp 310	engineered mutation

C: 1 - 238 (UniProt: Q84895)

PDB	External Database	Details
Tyr 19	His 359	engineered mutation
Phe 85	Leu 425	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	97500.9
Non-Polymers*	Number of molecules	2
	Total formula weight	688.7
All*	Total formula weight	98189.6

*Water molecules are not included.