8A66
Crystal structure of MST2 in complex with XMU-MP-1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Serine/threonine-protein kinase 3 36kDa subunit | polymer | 298 | 33923.9 | 1 | UniProt (Q13188) Pfam (PF00069) In PDB | Homo sapiens (human) | MST2/N |
| 2 | B | Serine/threonine-protein kinase 3 36kDa subunit | polymer | 298 | 34083.8 | 1 | UniProt (Q13188) Pfam (PF00069) In PDB | Homo sapiens (human) | MST2/N |
| 3 | A, B | 4-[(5,10-dimethyl-6-oxo-6,10-dihydro-5H-pyrimido[5,4-b]thieno[3,2-e][1,4]diazepin-2-yl)amino]benzenesulfonamide | non-polymer | 416.5 | 2 | Chemie (5BS) | |||
| 4 | A | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 5 | water | water | 18.0 | 215 | Chemie (HOH) |
Sequence modifications
A: 118 - 414 (UniProt: Q13188)
B: 118 - 416 (UniProt: Q13188)
| PDB | External Database | Details |
|---|---|---|
| Gly 117 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 117 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 68007.7 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 878.9 | |
| All* | Total formula weight | 68886.6 |
