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7Y26

Cryo-EM structure of the octreotide-bound SSTR2-miniGq-scFv16 complex

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1AGuanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1polymer33837198.71UniProt (P62873)
Pfam (PF00400)
In PDB
Homo sapiens (human)Transducin beta chain 1
2BEngineered Guanine nucleotide-binding protein G(q) subunit alphapolymer24327809.51Homo sapiens (human)
3COctreotidepolymer81036.21Homo sapiens
4Dsingle Fab chain (svFv16)polymer25827713.91Homo sapiens (human)
5ESomatostatin receptor type 2polymer33737759.81UniProt (P30874)
Pfam (PF00001)
In PDB
Homo sapiens (human)SS-2-R,SS2-R,SS2R,SST2,SRIF-1
6FGuanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2polymer717845.11UniProt (P59768)
Pfam (PF00631)
In PDB
Homo sapiens (human)G gamma-I
Sequence modifications
F: 1 - 71 (UniProt: P59768)
PDBExternal DatabaseDetails
Ser 68Cys 68engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains6
Total formula weight139363.1
All*Total formula weight139363.1
*Water molecules are not included.

221051

PDB entries from 2024-06-12

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