7XYH
Crystal structure of CK2a2 complexed with AG1112
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Casein kinase II subunit alpha' | polymer | 339 | 40160.0 | 2 | UniProt (P19784) Pfam (PF00069) In PDB | Homo sapiens (human) | CK II alpha' |
| 2 | A, B | 5-azanyl-3-[(~{Z})-1-cyano-2-(1~{H}-indol-3-yl)ethenyl]-1~{H}-pyrazole-4-carbonitrile | non-polymer | 274.3 | 2 | Chemie (8BH) | |||
| 3 | A, B | 1,2-ETHANEDIOL | non-polymer | 62.1 | 12 | Chemie (EDO) | |||
| 4 | water | water | 18.0 | 164 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 334 (UniProt: P19784)
| PDB | External Database | Details |
|---|---|---|
| Gly -4 | - | expression tag |
| Pro -3 | - | expression tag |
| Leu -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 80320.0 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 1293.4 | |
| All* | Total formula weight | 81613.3 |
