7XL5

Crystal structure of the H42T/A85G/I86A mutant of a nadp-dependent alcohol dehydrogenase

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	NADP-dependent isopropanol dehydrogenase	polymer	358	38430.6	4	UniProt (P14941) Pfam (PF08240) Pfam (PF00107) In PDB	Thermoanaerobacter brockii
2		water	water		18.0	336	Chemie (HOH)

Sequence modifications

A, B, C, D: 2 - 352 (UniProt: P14941)

PDB	External Database	Details
Met -5	-	initiating methionine
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag
His 1	-	expression tag
Thr 42	His 42	engineered mutation
Gly 85	Ala 85	engineered mutation
Ala 86	Ile 86	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	153722.4
All*	Total formula weight	153722.4

*Water molecules are not included.