7XL5

Crystal structure of the H42T/A85G/I86A mutant of a nadp-dependent alcohol dehydrogenase

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008270	molecular_function	zinc ion binding
A	0016491	molecular_function	oxidoreductase activity
A	0046872	molecular_function	metal ion binding
A	0050009	molecular_function	isopropanol dehydrogenase (NADP+) activity
B	0008270	molecular_function	zinc ion binding
B	0016491	molecular_function	oxidoreductase activity
B	0046872	molecular_function	metal ion binding
B	0050009	molecular_function	isopropanol dehydrogenase (NADP+) activity
C	0008270	molecular_function	zinc ion binding
C	0016491	molecular_function	oxidoreductase activity
C	0046872	molecular_function	metal ion binding
C	0050009	molecular_function	isopropanol dehydrogenase (NADP+) activity
D	0008270	molecular_function	zinc ion binding
D	0016491	molecular_function	oxidoreductase activity
D	0046872	molecular_function	metal ion binding
D	0050009	molecular_function	isopropanol dehydrogenase (NADP+) activity

Functional Information from PROSITE/UniProt

site_id	PS00059
Number of Residues	15
Details	ADH_ZINC Zinc-containing alcohol dehydrogenases signature. GHEaVGEvvevGseV

Chain	Residue	Details
A	GLY58-VAL72

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	BINDING: BINDING => ECO:0000269|PubMed:20102159, ECO:0000269|PubMed:9836873

Chain	Residue	Details
A	CYS37
A	HIS59
A	ASP150
B	CYS37
B	HIS59
B	ASP150
C	CYS37
C	HIS59
C	ASP150
D	CYS37
D	HIS59
D	ASP150

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site_id	SWS_FT_FI2
Number of Residues	20
Details	BINDING: BINDING => ECO:0000269|PubMed:9836873

Chain	Residue	Details
A	ILE175
A	GLY198
A	TYR218
A	VAL265
A	LYS340
B	ILE175
B	GLY198
B	TYR218
B	VAL265
B	LYS340
C	ILE175
C	GLY198
C	TYR218
C	VAL265
C	LYS340
D	ILE175
D	GLY198
D	TYR218
D	VAL265
D	LYS340

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