7WRQ
Structure of Human IGF1/IGFBP3/ALS Ternary Complex
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Insulin-like growth factor-binding protein complex acid labile subunit | polymer | 578 | 63312.3 | 1 | UniProt (P35858) Pfam (PF01462) Pfam (PF13855) In PDB | Homo sapiens (human) | ALS |
2 | B | Insulin-like growth factor-binding protein 3 | polymer | 264 | 28794.7 | 1 | UniProt (P17936) Pfam (PF00219) Pfam (PF00086) In PDB | Homo sapiens (human) | IBP-3,IGF-binding protein 3,IGFBP-3 |
3 | C | Isoform 3 of Insulin-like growth factor I | polymer | 70 | 7663.8 | 1 | UniProt (P05019) Pfam (PF00049) In PDB | Homo sapiens (human) | IGF-I,Mechano growth factor,MGF,Somatomedin-C |
4 | D | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G15407YE) | |||
5 | A | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 4 | Chemie (NAG) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 99770.8 | |
Branched | Number of molecules | 1 |
Total formula weight | 586.5 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 884.8 | |
All* | Total formula weight | 101242.2 |