7SHN

Cryo-EM structure of oleoyl-CoA-bound human peroxisomal fatty acid transporter ABCD1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	ATP-binding cassette sub-family D member 1	polymer	715	79606.8	2	UniProt (P33897) Pfam (PF06472) Pfam (PF00005) In PDB	Homo sapiens (Human)	Adrenoleukodystrophy protein,ALDP
2	A, B	S-{(3R,5R,9R)-1-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]-3,5,9-trihydroxy-8,8-dimethyl-3,5-dioxido-10,14-dioxo-2,4,6-trioxa-11,15-diaza-3lambda~5~,5lambda~5~-diphosphaheptadecan-17-yl} (9Z)-octadec-9-enethioate (non-preferred name)	non-polymer		1032.0	2	Chemie (3VV)

Sequence modifications

A, B: 2 - 686 (UniProt: P33897)

PDB	External Database	Details
Met -7	-	expression tag
Asp -6	-	expression tag
Tyr -5	-	expression tag
Lys -4	-	expression tag
Asp -3	-	expression tag
Asp -2	-	expression tag
Asp -1	-	expression tag
Asp 0	-	expression tag
Lys 1	-	expression tag
Gln 630	Glu 630	engineered mutation

A, B: 687 - 707 (PDB: 7SHN)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	159213.7
Non-Polymers*	Number of molecules	2
	Total formula weight	2064.0
All*	Total formula weight	161277.6

*Water molecules are not included.