7SCE
Ternary complex of fixed-arm Trx-3ost5 (I299E) with 8mer-2 octasaccharide substrate and co-factor product PAP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Thioredoxin 1,Heparan sulfate glucosamine 3-O-sulfotransferase 5 | polymer | 372 | 42821.4 | 1 | UniProt (P0AA25) UniProt (Q8IZT8) Pfam (PF00085) Pfam (PF00685) In PDB | Escherichia coli | Trx-1,Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 5,3-OST-5,Heparan sulfate 3-O-sulfotransferase 5,h3-OST-5 |
| 2 | C | 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid | branched | 1590.3 | 1 | In PDB | |||
| 3 | A | ADENOSINE-3'-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (A3P) | |||
| 4 | water | water | 18.0 | 53 | Chemie (HOH) |
Sequence modifications
A: 1 - 108 (UniProt: P0AA25)
A: 1086 - 1346 (UniProt: Q8IZT8)
| PDB | External Database | Details |
|---|---|---|
| Ala 109 | - | linker |
| Ala 110 | - | linker |
| Ala 111 | - | linker |
| PDB | External Database | Details |
|---|---|---|
| Glu 1299 | Ile 299 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 42821.4 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 1590.3 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 427.2 | |
| All* | Total formula weight | 44838.9 |
