7RD5
Crystal structure of Tspan15 large extracellular loop (Tspan15 LEL) in complex with 1C12 Fab
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C | 1C12 Fab Light Chain | polymer | 220 | 24295.9 | 2 | Mus musculus (mouse) | ||
| 2 | B, D | 1C12 Fab Heavy Chain | polymer | 226 | 24570.7 | 2 | Mus musculus (mouse) | ||
| 3 | F, E | Tetraspanin-15 | polymer | 122 | 14345.2 | 2 | UniProt (O95858) Pfam (PF00335) In PDB | Homo sapiens (Human) | Tspan-15,Tetraspan NET-7,Transmembrane 4 superfamily member 15 |
Sequence modifications
F, E: 115 - 230 (UniProt: O95858)
| PDB | External Database | Details |
|---|---|---|
| Gln 118 | Asn 118 | engineered mutation |
| Asp 189 | Asn 189 | engineered mutation |
| Leu 231 | - | expression tag |
| Glu 232 | - | expression tag |
| Val 233 | - | expression tag |
| Leu 234 | - | expression tag |
| Phe 235 | - | expression tag |
| Gln 236 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 126423.6 | |
| All* | Total formula weight | 126423.6 |
