7PWZ
Crystal structure of 14-3-3 sigma in complex with a C-terminal Estrogen Receptoralpha phosphopeptide, stabilised by Pyrrolidone1 derivative 228
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | 14-3-3 protein sigma | polymer | 236 | 26542.9 | 1 | UniProt (P31947) Pfam (PF00244) In PDB | Homo sapiens (Human) | Epithelial cell marker protein 1,Stratifin |
2 | B | C-terminus of Estrogen receptor alpha | polymer | 8 | 870.8 | 1 | UniProt (by SIFTS) (P03372) In PDB | Homo sapiens | |
3 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
4 | A | 2-oxidanyl-5-[(2~{R})-4-oxidanyl-5-oxidanylidene-2-(1-oxidanylidene-3~{H}-2-benzofuran-5-yl)-3-(phenylcarbonyl)-2~{H}-pyrrol-1-yl]benzoic acid | non-polymer | 471.4 | 1 | Chemie (8CQ) | |||
5 | water | water | 18.0 | 186 | Chemie (HOH) |
Sequence modifications
A: 1 - 231 (UniProt: P31947)
PDB | External Database | Details |
---|---|---|
Gly -4 | - | expression tag |
Ala -3 | - | expression tag |
Met -2 | - | expression tag |
Gly -1 | - | expression tag |
Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 27413.8 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 495.7 | |
All* | Total formula weight | 27909.5 |