7PR6
Crystal structure of E. coli beta-glucuronidase in complex with covalent inhibitor ME727
This is a non-PDB format compatible entry.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | AAA, BBB | Beta-glucuronidase | polymer | 601 | 68375.5 | 2 | UniProt (P05804) Pfam (PF02837) Pfam (PF00703) Pfam (PF02836) In PDB | Escherichia coli (strain K12) | GUS,Beta-D-glucuronoside glucuronosohydrolase |
2 | AAA, BBB | (2R,3S,5R,6R)-2,3,4,5,6-pentakis(oxidanyl)cyclohexane-1-carboxylic acid | non-polymer | 208.2 | 2 | Chemie (8I4) | |||
3 | water | water | 18.0 | 469 | Chemie (HOH) |
Sequence modifications
AAA, BBB: 18 - 599 (UniProt: P05804)
PDB | External Database | Details |
---|---|---|
Ser -1 | - | expression tag |
His 0 | - | expression tag |
Met 1 | - | expression tag |
Leu 2 | - | expression tag |
Arg 3 | - | expression tag |
Pro 4 | - | expression tag |
Val 5 | - | expression tag |
Glu 6 | - | expression tag |
Thr 7 | - | expression tag |
Pro 8 | - | expression tag |
Thr 9 | - | expression tag |
Arg 10 | - | expression tag |
Glu 11 | - | expression tag |
Ile 12 | - | expression tag |
Lys 13 | - | expression tag |
Lys 14 | - | expression tag |
Leu 15 | - | expression tag |
Asp 16 | - | expression tag |
Gly 17 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 136751.1 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 416.3 | |
All* | Total formula weight | 137167.4 |