7OY6
Crystal structure of human DYRK1A in complex with ARN25068
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | C | Dual specificity tyrosine-phosphorylation-regulated kinase 1A | polymer | 359 | 41863.3 | 1 | UniProt (Q13627) Pfam (PF00069) In PDB | Homo sapiens (Human) | Dual specificity YAK1-related kinase,HP86,Protein kinase minibrain homolog,MNBH,hMNB |
| 2 | C | ~{N}4-(3-cyclopropyl-1~{H}-pyrazol-5-yl)-~{N}2-(phenylmethyl)thieno[3,2-d]pyrimidine-2,4-diamine | non-polymer | 362.5 | 1 | Chemie (39I) | |||
| 3 | water | water | 18.0 | 29 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 41863.3 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 362.5 | |
| All* | Total formula weight | 42225.7 |
