7N1V
Structural basis for enhanced infectivity and immune evasion of SARS-CoV-2 variants
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C | Spike glycoprotein | polymer | 1305 | 144368.5 | 3 | UniProt (P0DTC2) Pfam (PF16451) Pfam (PF09408) Pfam (PF19209) Pfam (PF01601) In PDB | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2) | S glycoprotein,E2,Peplomer protein |
| 2 | a, b, c, D, E... | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 20 | In PDB GlyTouCan (G42666HT) | |||
| 3 | d, I, S | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 570.5 | 3 | In PDB GlyTouCan (G21290RB) | |||
| 4 | e, f, J, K, T... | alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 6 | In PDB GlyTouCan (G62182OO) | |||
| 5 | C, A, B | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 28 | Chemie (NAG) |
Sequence modifications
A, B, C: 1 - 1273 (UniProt: P0DTC2)
| PDB | External Database | Details |
|---|---|---|
| - | His 69 | deletion |
| - | Val 70 | deletion |
| - | Tyr 144 | deletion |
| Tyr 501 | Asn 501 | conflict |
| Asp 570 | Ala 570 | conflict |
| Gly 614 | Asp 614 | conflict |
| His 681 | Pro 681 | conflict |
| Ile 716 | Thr 716 | conflict |
| Ala 982 | Ser 982 | conflict |
| His 1118 | Asp 1118 | conflict |
| Ser 1274 | - | expression tag |
| Gly 1275 | - | expression tag |
| Gly 1276 | - | expression tag |
| Gly 1277 | - | expression tag |
| Ser 1278 | - | expression tag |
| Ala 1279 | - | expression tag |
| Trp 1280 | - | expression tag |
| Ser 1281 | - | expression tag |
| His 1282 | - | expression tag |
| Pro 1283 | - | expression tag |
| Gln 1284 | - | expression tag |
| Phe 1285 | - | expression tag |
| Glu 1286 | - | expression tag |
| Lys 1287 | - | expression tag |
| Gly 1288 | - | expression tag |
| Gly 1289 | - | expression tag |
| Gly 1290 | - | expression tag |
| Ser 1291 | - | expression tag |
| Gly 1292 | - | expression tag |
| Gly 1293 | - | expression tag |
| Gly 1294 | - | expression tag |
| Ser 1295 | - | expression tag |
| Gly 1296 | - | expression tag |
| Gly 1297 | - | expression tag |
| Ser 1298 | - | expression tag |
| Ser 1299 | - | expression tag |
| Ala 1300 | - | expression tag |
| Trp 1301 | - | expression tag |
| Ser 1302 | - | expression tag |
| His 1303 | - | expression tag |
| Pro 1304 | - | expression tag |
| Gln 1305 | - | expression tag |
| Phe 1306 | - | expression tag |
| Glu 1307 | - | expression tag |
| Lys 1308 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 433105.5 | |
| Branched | Number of molecules | 29 |
| Total formula weight | 13718.9 | |
| Non-Polymers* | Number of molecules | 28 |
| Total formula weight | 6193.8 | |
| All* | Total formula weight | 453018.2 |
