7MNZ
Crystal Structure of Nup358/RanBP2 Ran-binding domain 4 in complex with Ran-GPPNHP
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C, E, G, I... | GTP-binding nuclear protein Ran | polymer | 216 | 24430.0 | 6 | UniProt (P62826) Pfam (PF00071) In PDB | Homo sapiens (Human) | Androgen receptor-associated protein 24,GTPase Ran,Ras-like protein TC4,Ras-related nuclear protein |
2 | B, D, F, H, J... | E3 SUMO-protein ligase RanBP2 | polymer | 139 | 16188.4 | 6 | UniProt (P49792) Pfam (PF00638) In PDB | Homo sapiens (Human) | 358 kDa nucleoporin,Nuclear pore complex protein Nup358,Nucleoporin Nup358,Ran-binding protein 2,RanBP2,p270 |
3 | A, C, E, G, I... | PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | non-polymer | 522.2 | 6 | Chemie (GNP) | |||
4 | A, C, E, G, I... | MAGNESIUM ION | non-polymer | 24.3 | 6 | Chemie (MG) | |||
5 | water | water | 18.0 | 473 | Chemie (HOH) |
Sequence modifications
A, C, E, G, I, K: 1 - 215 (UniProt: P62826)
B, D, F, H, J, L: 2911 - 3045 (UniProt: P49792)
PDB | External Database | Details |
---|---|---|
Ser 0 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Gly 2907 | - | expression tag |
Pro 2908 | - | expression tag |
Gly 2909 | - | expression tag |
Ser 2910 | - | expression tag |
Gln 2962 | Trp 2962 | engineered mutation |
Asn 2963 | His 2963 | engineered mutation |
Tyr 2964 | Thr 2964 | engineered mutation |
Asp 2965 | Met 2965 | engineered mutation |
Asn 2966 | Lys 2966 | engineered mutation |
Lys 2967 | Asn 2967 | engineered mutation |
Gln 2968 | Tyr 2968 | engineered mutation |
Val 2969 | Tyr 2969 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 12 |
Total formula weight | 243710.8 | |
Non-Polymers* | Number of molecules | 12 |
Total formula weight | 3279.0 | |
All* | Total formula weight | 246989.8 |