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7MGQ

AICAR transformylase/IMP cyclohydrolase (ATIC) is essential for de novo purine biosynthesis and infection by Cryptococcus neoformans

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D5-aminoimidazole-4-carboxamide ribonucleotide formyltransferasepolymer60565483.74UniProt (A0A225ZZG7)
Pfam (PF02142)
Pfam (PF01808)
In PDB
Cryptococcus neoformansAICAR transformylase,IMP synthase,Inosinicase,Phosphoribosylaminoimidazolecarboxamide formyltransferase
2A, B, C, DMAGNESIUM IONnon-polymer24.34Chemie (MG)
3waterwater18.074Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight261934.9
Non-Polymers*Number of molecules4
Total formula weight97.2
All*Total formula weight262032.1
*Water molecules are not included.

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PDB entries from 2024-06-12

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