7M8H
Structure of Memo1 C244S metal binding site mutant at 1.75A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | Protein MEMO1 | polymer | 294 | 33425.7 | 4 | UniProt (Q9Y316) Pfam (PF01875) In PDB | Homo sapiens (Human) | C21orf19-like protein,Hepatitis C virus NS5A-transactivated protein 7,HCV NS5A-transactivated protein 7,Mediator of ErbB2-driven cell motility 1,Mediator of cell motility 1,Memo-1 |
| 2 | A, C, D, B | GLUTATHIONE | non-polymer | 307.3 | 4 | Chemie (GSH) | |||
| 3 | C, A, D, B | 1,2-ETHANEDIOL | non-polymer | 62.1 | 32 | Chemie (EDO) | |||
| 4 | A, D | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | non-polymer | 195.2 | 3 | Chemie (MES) | |||
| 5 | C, A, D | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 3 | Chemie (PEG) | |||
| 6 | C, B, D | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 7 | water | water | 18.0 | 1368 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 4 - 297 (UniProt: Q9Y316)
| PDB | External Database | Details |
|---|---|---|
| Ser 244 | Cys 244 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 133702.8 | |
| Non-Polymers* | Number of molecules | 45 |
| Total formula weight | 4395.8 | |
| All* | Total formula weight | 138098.6 |
