7F0I

phosphodiesterase-9A in complex with inhibitor 4b

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Isoform PDE9A2 of High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A	polymer	533	61789.1	2	UniProt (O76083-2) Pfam (PF00233) UniProt (by SIFTS) (O76083) In PDB	Homo sapiens (Human)
2	A, B	ZINC ION	non-polymer		65.4	2	Chemie (ZN)
3	A, B	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
4	A, B	1-cyclopentyl-6-[[(2R)-1-(6-fluoranyl-2-azaspiro[3.3]heptan-2-yl)-1-oxidanylidene-propan-2-yl]amino]-5H-pyrazolo[3,4-d]pyrimidin-4-one	non-polymer		388.4	2	Chemie (06A)
5		water	water		18.0	116	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	123578.2
Non-Polymers*	Number of molecules	6
	Total formula weight	956.3
All*	Total formula weight	124534.5

*Water molecules are not included.