7EZR
Indole-2-carboxylic acid derivatives as allosteric inhibitors of fructose-1,6-bisphosphatase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | Fructose-1,6-bisphosphatase 1 | polymer | 338 | 36887.4 | 4 | UniProt (P09467) Pfam (PF00316) Pfam (PF18913) In PDB | Homo sapiens (Human) | FBPase 1,D-fructose-1,6-bisphosphate 1-phosphohydrolase 1,Liver FBPase |
| 2 | A, B, C, D | 5-ethyl-7-nitro-3-[3-oxidanylidene-3-(thiophen-2-ylsulfonylamino)propyl]-1H-indole-2-carboxylic acid | non-polymer | 451.5 | 4 | Chemie (0H1) | |||
| 3 | A, B, C, D | 1,6-di-O-phosphono-beta-D-fructofuranose | non-polymer | 340.1 | 4 | Chemie (FBP) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 147549.7 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 3166.4 | |
| All* | Total formula weight | 150716.1 |
