7DTU
Human Calcium-Sensing Receptor bound with L-Trp
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Extracellular calcium-sensing receptor | polymer | 1099 | 123520.8 | 2 | UniProt (P41180) Pfam (PF01094) Pfam (PF07562) Pfam (PF00003) In PDB | Homo sapiens (Human) | hCasR,Parathyroid cell calcium-sensing receptor 1,PCaR1 |
| 2 | C, D, E, F | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 4 | In PDB GlyTouCan (G42666HT) | |||
| 3 | A, B | TRYPTOPHAN | non-polymer | 204.2 | 2 | Chemie (TRP) | |||
| 4 | A, B | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 6 | Chemie (NAG) |
Sequence modifications
A, B: 20 - 1078 (UniProt: P41180)
| PDB | External Database | Details |
|---|---|---|
| Met -10 | - | initiating methionine |
| Lys -9 | - | expression tag |
| Thr -8 | - | expression tag |
| Ile -7 | - | expression tag |
| Ile -6 | - | expression tag |
| Ala -5 | - | expression tag |
| Leu -4 | - | expression tag |
| Ser -3 | - | expression tag |
| Tyr -2 | - | expression tag |
| Ile -1 | - | expression tag |
| Phe 0 | - | expression tag |
| Cys 1 | - | expression tag |
| Leu 2 | - | expression tag |
| Val 3 | - | expression tag |
| Phe 4 | - | expression tag |
| Ala 5 | - | expression tag |
| Asp 6 | - | expression tag |
| Tyr 7 | - | expression tag |
| Lys 8 | - | expression tag |
| Asp 9 | - | expression tag |
| Asp 10 | - | expression tag |
| Asp 11 | - | expression tag |
| Asp 12 | - | expression tag |
| Glu 13 | - | expression tag |
| Asn 14 | - | expression tag |
| Leu 15 | - | expression tag |
| Tyr 16 | - | expression tag |
| Phe 17 | - | expression tag |
| Gln 18 | - | expression tag |
| Gly 19 | - | expression tag |
| His 1079 | - | expression tag |
| His 1080 | - | expression tag |
| His 1081 | - | expression tag |
| His 1082 | - | expression tag |
| His 1083 | - | expression tag |
| His 1084 | - | expression tag |
| His 1085 | - | expression tag |
| His 1086 | - | expression tag |
| His 1087 | - | expression tag |
| His 1088 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 247041.7 | |
| Branched | Number of molecules | 4 |
| Total formula weight | 1697.6 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1735.7 | |
| All* | Total formula weight | 250475.0 |
