6Z1A
Ternary complex of Staphylococcus aureus DNA gyrase with AMK12 and DNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | B, D | DNA gyrase subunit B,DNA gyrase subunit A | polymer | 692 | 78079.0 | 2 | UniProt (P0A0K8) UniProt (P20831) Pfam (PF01751) Pfam (PF00986) Pfam (PF00521) In PDB | Staphylococcus aureus | |
| 2 | E, F | DNA (5'-D(*AP*GP*CP*CP*GP*TP*AP*G)-3') | polymer | 8 | 2451.6 | 2 | Staphylococcus aureus subsp. aureus N315 | ||
| 3 | G, H | DNA (5'-D(P*GP*TP*AP*CP*CP*TP*AP*CP*GP*GP*CP*T)-3') | polymer | 12 | 3638.4 | 2 | Staphylococcus aureus subsp. aureus N315 | ||
| 4 | B, D | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | non-polymer | 238.3 | 2 | Chemie (EPE) | |||
| 5 | B, D, G | MANGANESE (II) ION | non-polymer | 54.9 | 4 | Chemie (MN) | |||
| 6 | D, E | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 3 | Chemie (DMS) | |||
| 7 | D | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 8 | G | ~{N}-[(4-chlorophenyl)methyl]-1-[2-(6-methoxy-1,5-naphthyridin-4-yl)ethyl]piperidin-4-amine | non-polymer | 410.9 | 1 | Chemie (Q52) | |||
| 9 | water | water | 18.0 | 343 | Chemie (HOH) |
Sequence modifications
B, D: 410 - 1001 (UniProt: P0A0K8)
B, D: 1002 - 1491 (UniProt: P20831)
| PDB | External Database | Details |
|---|---|---|
| Met 409 | - | initiating methionine |
| - | Leu 544 | deletion |
| - | Tyr 545 | deletion |
| - | Lys 546 | deletion |
| - | Leu 547 | deletion |
| - | Thr 548 | deletion |
| - | Gln 549 | deletion |
| - | Gly 550 | deletion |
| - | Lys 551 | deletion |
| - | Gln 552 | deletion |
| - | Lys 553 | deletion |
| - | Tyr 554 | deletion |
| - | Tyr 555 | deletion |
| - | Val 556 | deletion |
| - | Tyr 557 | deletion |
| - | Asn 558 | deletion |
| - | Asp 559 | deletion |
| - | Arg 560 | deletion |
| - | Glu 561 | deletion |
| - | Leu 562 | deletion |
| - | Asp 563 | deletion |
| - | Lys 564 | deletion |
| - | Leu 565 | deletion |
| - | Lys 566 | deletion |
| - | Ser 567 | deletion |
| - | Glu 568 | deletion |
| - | Leu 569 | deletion |
| - | Asn 570 | deletion |
| - | Pro 571 | deletion |
| - | Thr 572 | deletion |
| - | Pro 573 | deletion |
| - | Lys 574 | deletion |
| - | Trp 575 | deletion |
| - | Ser 576 | deletion |
| - | Ile 577 | deletion |
| Thr 544 | Ala 578 | conflict |
| Gly 545 | Arg 579 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Phe 1123 | Tyr 123 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 168338.0 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 1377.2 | |
| All* | Total formula weight | 169715.1 |
