6VM9

T4H2 T cell receptor bound to HLA-A2 presenting gp100T2M peptide (IMDQVPFSV)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	MHC class I antigen, A-2 alpha chain	polymer	275	31854.2	1	UniProt (A0A5B8RNS7) Pfam (PF00129) Pfam (PF07654) UniProt (by SIFTS) (A0A140T913) In PDB	Homo sapiens (Human)
2	B	Beta-2-microglobulin	polymer	100	11879.4	1	UniProt (P61769) Pfam (PF07654) In PDB	Homo sapiens (Human)
3	C	Melanocyte protein PMEL	polymer	9	1035.2	1	UniProt (P40967) In PDB	Homo sapiens	ME20-M,ME20M,Melanocyte protein Pmel 17,Melanocytes lineage-specific antigen GP100,Melanoma-associated ME20 antigen,P1,P100,Premelanosome protein,Silver locus protein homolog
4	D	T4H2 T cell receptor alpha chain	polymer	206	22769.0	1		Homo sapiens (Human)
5	E	T4H2 T cell receptor beta chain	polymer	241	27427.5	1		Homo sapiens (Human)

Sequence modifications

B: 2 - 100 (UniProt: P61769)

PDB	External Database	Details
Met 1	-	initiating methionine

C: 1 - 9 (UniProt: P40967)

PDB	External Database	Details
Met 2	Thr 210	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	5
	Total formula weight	94965.2
All*	Total formula weight	94965.2

*Water molecules are not included.