6TVS

Crystal structure of the haemagglutinin mutant (Gln226Leu) from an H10N7 seal influenza virus isolated in Germany in complex with avian receptor analogue 3'-SLN

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	C, E, K	Hemagglutinin HA1	polymer	325	35484.1	3	UniProt (A0A0A7HR51) Pfam (PF00509) In PDB	Influenza A virus (A/harbour seal/Germany/1/2014(H10N7))
2	D, F, L	Hemagglutinin HA2	polymer	177	20313.4	3	UniProt (A0A0A7HR51) Pfam (PF00509) In PDB	Influenza A virus (A/harbour seal/Germany/1/2014(H10N7))
3	A, G	N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose	branched		471.4	2	In PDB GlyTouCan (G30207PZ)
4	B	N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		674.6	1	In PDB BIRD (PRD_900067) GlyTouCan (G00065MO)		3'-sialyl-N-acetyllactosamine
5	L, C, D, E, F...	1,2-ETHANEDIOL	non-polymer		62.1	13	Chemie (EDO)
6	D, E, F, L	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	4	Chemie (NAG)
7	K	CALCIUM ION	non-polymer		40.1	1	Chemie (CA)
8		water	water		18.0	1153	Chemie (HOH)

Sequence modifications

C, E, K: 3 - 325 (UniProt: A0A0A7HR51)

PDB	External Database	Details
Asp 1	-	expression tag
Pro 2	-	expression tag

D, F, L: 1 - 176 (UniProt: A0A0A7HR51)

PDB	External Database	Details
Lys 177	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	167392.5
Branched	Number of molecules	3
	Total formula weight	1617.4
Non-Polymers*	Number of molecules	18
	Total formula weight	1731.8
All*	Total formula weight	170741.7

*Water molecules are not included.