6NEW

Apo structure of the activated truncation of Vav1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Proto-oncogene vav	polymer	421	49679.9	1	UniProt (P15498) Pfam (PF00621) Pfam (PF00169) Pfam (PF00130) In PDB	Homo sapiens (Human)	Vav1 vav guanine nucleotide exchange factor 1
2	A	ZINC ION	non-polymer		65.4	2	Chemie (ZN)
3		water	water		18.0	195	Chemie (HOH)

Sequence modifications

A: 170 - 575 (UniProt: P15498)

PDB	External Database	Details
Met 155	-	expression tag
Gly 156	-	expression tag
Lys 157	-	expression tag
His 158	-	expression tag
His 159	-	expression tag
His 160	-	expression tag
His 161	-	expression tag
His 162	-	expression tag
His 163	-	expression tag
Glu 164	-	expression tag
Asn 165	-	expression tag
Leu 166	-	expression tag
Tyr 167	-	expression tag
Phe 168	-	expression tag
Gln 169	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	49679.9
Non-Polymers*	Number of molecules	2
	Total formula weight	130.8
All*	Total formula weight	49810.7

*Water molecules are not included.