6KMS
Crystal structure of human N6amt1-Trm112 in complex with SAM (space group I422)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | C, D | Methyltransferase N6AMT1 | polymer | 228 | 24878.4 | 2 | UniProt (Q9Y5N5) Pfam (PF05175) In PDB | Homo sapiens (Human) | HemK methyltransferase family member 2,M.HsaHemK2P,Methylarsonite methyltransferase N6AMT1,N(6)-adenine-specific DNA methyltransferase 1,Protein N(5)-glutamine methyltransferase |
2 | A, B | Multifunctional methyltransferase subunit TRM112-like protein | polymer | 126 | 14627.9 | 2 | UniProt (Q9UI30) Pfam (PF03966) In PDB | Homo sapiens (Human) | tRNA methyltransferase 112 homolog |
3 | C, D | S-ADENOSYLMETHIONINE | non-polymer | 398.4 | 2 | Chemie (SAM) |
Sequence modifications
C, D: 1 - 214 (UniProt: Q9Y5N5)
A, B: 1 - 125 (UniProt: Q9UI30)
PDB | External Database | Details |
---|---|---|
Mse -13 | - | expression tag |
Gly -12 | - | expression tag |
Ser -11 | - | expression tag |
Ser -10 | - | expression tag |
His -9 | - | expression tag |
His -8 | - | expression tag |
His -7 | - | expression tag |
His -6 | - | expression tag |
His -5 | - | expression tag |
His -4 | - | expression tag |
Ser -3 | - | expression tag |
Gln -2 | - | expression tag |
Asp -1 | - | expression tag |
Pro 0 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Mse 0 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 79012.7 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 796.9 | |
All* | Total formula weight | 79809.6 |