6FS7

Influenza A/California/04/2009 (pH1N1) endonuclease with I38T mutation with bound inhibitor, baloxavir acid (BXA)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E...	Polymerase acidic protein,Polymerase acidic protein	polymer	193	22513.7	6	UniProt (C3W5S0) In PDB	Influenza A virus (A/California/04/2009(H1N1))	RNA-directed RNA polymerase subunit P2,RNA-directed RNA polymerase subunit P2
2	A, B, C, D, E...	MANGANESE (II) ION	non-polymer		54.9	12	Chemie (MN)
3	A, B, C, D, E...	Baloxavir acid	non-polymer		483.5	6	Chemie (E4Z)
4		water	water		18.0	503	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F: 1 - 51 (UniProt: C3W5S0)

PDB	External Database	Details
Gly -6	-	expression tag
Met -5	-	expression tag
Gly -4	-	expression tag
Ser -3	-	expression tag
Gly -2	-	expression tag
Met -1	-	expression tag
Ala 0	-	expression tag
Thr 38	Ile 38	engineered mutation

A, B, C, D, E, F: 65 - 198 (UniProt: C3W5S0)

PDB	External Database	Details
Gly 64	-	linker

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	135082.0
Non-Polymers*	Number of molecules	18
	Total formula weight	3560.2
All*	Total formula weight	138642.2

*Water molecules are not included.