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6D7S

Cryo-EM structure of human TRPV6-Y467A in amphipols

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, DTransient receptor potential cation channel subfamily V member 6polymer74285076.94UniProt (Q9H1D0)
Pfam (PF12796)
Pfam (PF00023)
Pfam (PF00520)
In PDB
Homo sapiens (Human)TrpV6,CaT-like,CaT-L,Calcium transport protein 1,CaT1,Epithelial calcium channel 2,ECaC2
Sequence modifications
A, B, C, D: 1 - 725 (UniProt: Q9H1D0)
PDBExternal DatabaseDetails
Ala 467Tyr 507engineered mutation
Leu 726-expression tag
Val 727-expression tag
Pro 728-expression tag
Arg 729-expression tag
Gly 730-expression tag
Ser 731-expression tag
Ala 732-expression tag
Ala 733-expression tag
Ala 734-expression tag
Trp 735-expression tag
Ser 736-expression tag
His 737-expression tag
Pro 738-expression tag
Gln 739-expression tag
Phe 740-expression tag
Glu 741-expression tag
Lys 742-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight340307.4
All*Total formula weight340307.4
*Water molecules are not included.

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PDB entries from 2024-06-12

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