6CXC
3.9A Cryo-EM structure of murine antibody bound at a novel epitope of respiratory syncytial virus fusion protein
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | X, G, I | R4.C6 Fab Heavy Chain | polymer | 118 | 12831.4 | 3 | Mus musculus (Mouse) | ||
2 | Y, J, K | R4.C6 Fab Light Chain | polymer | 122 | 13457.2 | 3 | Mus musculus (Mouse) | ||
3 | A, B, C, D, E... | Fusion glycoprotein F0, Envelope glycoprotein chimera | polymer | 548 | 60728.0 | 6 | UniProt (P03420) UniProt (M1E1E4) Pfam (PF00523) Pfam (PF07921) In PDB | Human respiratory syncytial virus A (strain A2) | Protein F |
4 | A, B, C, D, E... | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 6 | Chemie (NAG) |
Sequence modifications
A, B, C, D, E, F: 26 - 526 (UniProt: P03420)
A, B, C, D, E, F: 538 - 567 (UniProt: M1E1E4)
PDB | External Database | Details |
---|---|---|
Ala 102 | Pro 102 | conflict |
Gln 133 | Arg 133 | conflict |
Gln 135 | Arg 135 | conflict |
Gln 136 | Arg 136 | conflict |
Val 379 | Ile 379 | conflict |
Val 447 | Met 447 | conflict |
Gly 527 | - | linker |
Ala 528 | - | linker |
Leu 529 | - | linker |
Val 530 | - | linker |
Pro 531 | - | linker |
Arg 532 | - | linker |
Gly 533 | - | linker |
Ser 534 | - | linker |
Pro 535 | - | linker |
Gly 536 | - | linker |
Ser 537 | - | linker |
PDB | External Database | Details |
---|---|---|
His 568 | - | expression tag |
His 569 | - | expression tag |
His 570 | - | expression tag |
His 571 | - | expression tag |
His 572 | - | expression tag |
His 573 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 12 |
Total formula weight | 443233.9 | |
Non-Polymers* | Number of molecules | 6 |
Total formula weight | 1327.2 | |
All* | Total formula weight | 444561.1 |