Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

6AEB

Crystal structure of xCas9 in complex with sgRNA and target DNA (AAG PAM)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, ERNA (95-MER)polymer10032269.22Streptococcus pyogenes
2C, GDNA (25-MER)polymer288558.62Streptococcus pyogenes
3D, HDNA (5'-D(*AP*AP*AP*AP*AP*GP*TP*AP*TP*TP*G)-3')polymer113405.32Streptococcus pyogenes
4B, FDNA Nucleasepolymer1368158538.82UniProt (Q99ZW2)
Pfam (PF16593)
Pfam (PF16592)
Pfam (PF13395)
Pfam (PF16595)
In PDB
Streptococcus pyogenes
5waterwater18.01Chemie (HOH)
Sequence modifications
B, F: 1 - 1368 (UniProt: Q99ZW2)
PDBExternal DatabaseDetails
Ala 10Asp 10engineered mutation
Thr 262Ala 262engineered mutation
Leu 324Arg 324engineered mutation
Ile 409Ser 409engineered mutation
Lys 480Glu 480engineered mutation
Asp 543Glu 543engineered mutation
Ile 694Met 694engineered mutation
Ala 840His 840engineered mutation
Val 1219Glu 1219engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains8
Total formula weight405543.8
All*Total formula weight405543.8
*Water molecules are not included.

221051

PDB entries from 2024-06-12

PDB statisticsPDBj update infoContact PDBjnumon