5ZIC

Crystal structure of human GnT-V luminal domain in complex with acceptor sugar

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A	polymer	523	59798.8	2	UniProt (Q09328) Pfam (PF15024) In PDB	Homo sapiens (Human)	Alpha-mannoside beta-1,6-N-acetylglucosaminyltransferase,GlcNAc-T V,GNT-V,Mannoside acetylglucosaminyltransferase 5,N-acetylglucosaminyl-transferase V
2	C, D	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-6-thio-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose	branched		561.6	2	In PDB GlyTouCan (G35411CV)
3		water	water		18.0	218	Chemie (HOH)

Sequence modifications

A, B: 213 - 340 (UniProt: Q09328)

PDB	External Database	Details
Gly 208	-	expression tag
Lys 209	-	expression tag
Asp 210	-	expression tag
Gly 211	-	expression tag
Ser 212	-	expression tag

A, B: 345 - 741 (UniProt: Q09328)

PDB	External Database	Details
Gly 341	-	linker
Gly 342	-	linker
Gly 343	-	linker
Gly 344	-	linker

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	119597.6
Branched	Number of molecules	2
	Total formula weight	1123.1
All*	Total formula weight	120720.7

*Water molecules are not included.