5XJT
Crystal Structure of the Gemin2-binding domain of SMN, Gemin2 in Complex with SmD1(1-82)/D2.R61A/F/E/G from Human
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | 2 | Gem-associated protein 2 | polymer | 280 | 31620.1 | 1 | UniProt (O14893) Pfam (PF04938) In PDB | Homo sapiens (Human) | Gemin-2,Component of gems 2,Survival of motor neuron protein-interacting protein 1,SMN-interacting protein 1 |
| 2 | A | Small nuclear ribonucleoprotein Sm D1 | polymer | 82 | 9301.0 | 1 | UniProt (P62314) Pfam (PF01423) In PDB | Homo sapiens (Human) | Sm-D1,Sm-D autoantigen,snRNP core protein D1 |
| 3 | B | Small nuclear ribonucleoprotein Sm D2 | polymer | 118 | 13465.8 | 1 | UniProt (P62316) Pfam (PF01423) In PDB | Homo sapiens (Human) | Sm-D2,snRNP core protein D2 |
| 4 | E | Small nuclear ribonucleoprotein E | polymer | 92 | 10817.6 | 1 | UniProt (P62304) Pfam (PF01423) In PDB | Homo sapiens (Human) | snRNP-E,Sm protein E,SmE |
| 5 | F | Small nuclear ribonucleoprotein F | polymer | 86 | 9734.2 | 1 | UniProt (P62306) Pfam (PF01423) In PDB | Homo sapiens (Human) | snRNP-F,Sm protein F,SmF |
| 6 | G | Small nuclear ribonucleoprotein G | polymer | 76 | 8508.1 | 1 | UniProt (P62308) Pfam (PF01423) In PDB | Homo sapiens (Human) | snRNP-G,Sm protein G,SmG |
| 7 | M | Survival motor neuron protein | polymer | 37 | 4047.4 | 1 | UniProt (Q16637) Pfam (PF20636) In PDB | Homo sapiens (Human) | Component of gems 1,Gemin-1 |
Sequence modifications
B: 1 - 118 (UniProt: P62316)
| PDB | External Database | Details |
|---|---|---|
| Ala 61 | Arg 61 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 7 |
| Total formula weight | 87494.1 | |
| All* | Total formula weight | 87494.1 |
