5W8V
HUMAN HGPRT in complex with [(2-[(guanin-9-yl)methyl]propane-1,3-diyl)bis(oxy)]bis(methylene)diphosphonic acid
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | Hypoxanthine-guanine phosphoribosyltransferase | polymer | 215 | 24222.9 | 4 | UniProt (P00492) Pfam (PF00156) In PDB | Homo sapiens (Human) | HGPRTase |
| 2 | A, B, C, D | {[(2R)-2-[(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)methyl]-3-(2-phosphonoethoxy)propoxy]methyl}phosphonic acid | non-polymer | 441.3 | 4 | Chemie (9YP) | |||
| 3 | A, B, C, D | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 4 | water | water | 18.0 | 521 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 4 - 217 (UniProt: P00492)
| PDB | External Database | Details |
|---|---|---|
| Ala 3 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 96891.7 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1862.3 | |
| All* | Total formula weight | 98754.0 |
