5TQ0
Crystal structure of amino terminal domains of the NMDA receptor subunit GluN1 and GluN2A in the presence of EDTA
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | NMDA glutamate receptor subunit | polymer | 391 | 43801.0 | 1 | UniProt (Q91977) Pfam (PF01094) UniProt (by SIFTS) (A0A1L8F5J9) In PDB | Xenopus laevis (African clawed frog) | |
2 | B | Glutamate receptor ionotropic, NMDA 2A | polymer | 360 | 40572.1 | 1 | UniProt (Q00959) Pfam (PF01094) In PDB | Rattus norvegicus (Rat) | GluN2A,Glutamate [NMDA] receptor subunit epsilon-1,N-methyl D-aspartate receptor subtype 2A,NR2A |
3 | H | FAB, HEAVY CHAIN | polymer | 221 | 23993.9 | 1 | Mus musculus (mouse) | ||
4 | L | FAB, LIGHT CHAIN | polymer | 214 | 23568.0 | 1 | Mus musculus | ||
5 | A | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
6 | A | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
7 | A, B, L | SULFATE ION | non-polymer | 96.1 | 12 | Chemie (SO4) | |||
8 | H | ISOPROPYL ALCOHOL | non-polymer | 60.1 | 1 | Chemie (IPA) | |||
9 | water | water | 18.0 | 50 | Chemie (HOH) |
Sequence modifications
A: 24 - 408 (UniProt: Q91977)
PDB | External Database | Details |
---|---|---|
Gln 61 | Asn 61 | engineered mutation |
Gln 371 | Asn 371 | engineered mutation |
Gly 409 | - | expression tag |
Thr 410 | - | expression tag |
Leu 411 | - | expression tag |
Val 412 | - | expression tag |
Pro 413 | - | expression tag |
Arg 414 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 131935.0 | |
Non-Polymers* | Number of molecules | 17 |
Total formula weight | 1839.5 | |
All* | Total formula weight | 133774.5 |