5PB0
Crystal Structure of Factor VIIa in complex with 2-(4-ethoxy-3-methoxyphenyl)-2-(isoquinolin-6-ylamino)acetic acid
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Coagulation factor VII light chain | polymer | 64 | 6984.9 | 1 | UniProt (P08709) Pfam (PF14670) In PDB | Homo sapiens (Human) | Proconvertin,Serum prothrombin conversion accelerator,SPCA |
| 2 | B | Coagulation factor VII heavy chain | polymer | 254 | 28103.3 | 1 | UniProt (P08709) Pfam (PF00089) In PDB | Homo sapiens (Human) | Proconvertin,Serum prothrombin conversion accelerator,SPCA |
| 3 | A, B | CHLORIDE ION | non-polymer | 35.5 | 3 | Chemie (CL) | |||
| 4 | A, B | SULFATE ION | non-polymer | 96.1 | 5 | Chemie (SO4) | |||
| 5 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 6 | B | (2~{R})-2-(4-ethoxy-3-methoxy-phenyl)-2-(isoquinolin-6-ylamino)ethanoic acid | non-polymer | 352.4 | 1 | Chemie (7LX) | |||
| 7 | B | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 8 | water | water | 18.0 | 355 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 35088.2 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 1071.2 | |
| All* | Total formula weight | 36159.4 |
