Functional Information from GO Data
| Chain | GOid | namespace | contents |
| B | 0004252 | molecular_function | serine-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 A 302 |
| Chain | Residue |
| A | CYS162 |
| A | SER163 |
| A | ASP164 |
| A | HOH420 |
| B | ARG331 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 303 |
| Chain | Residue |
| B | GLY414 |
| B | TRP416 |
| A | GLY196 |
| A | LYS197 |
| A | ILE198 |
| A | GLU202 |
| site_id | AC3 |
| Number of Residues | 16 |
| Details | binding site for residue 7LX B 501 |
| Chain | Residue |
| B | HIS253 |
| B | THR299 |
| B | PRO381 |
| B | ASP398 |
| B | SER399 |
| B | LYS401 |
| B | SER404 |
| B | VAL422 |
| B | SER423 |
| B | TRP424 |
| B | GLY425 |
| B | GLY427 |
| B | SO4506 |
| B | HOH623 |
| B | HOH655 |
| B | HOH754 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue CA B 502 |
| Chain | Residue |
| B | GLU270 |
| B | ASP272 |
| B | GLU275 |
| B | GLU280 |
| B | HOH644 |
| B | HOH762 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | binding site for residue CL B 504 |
| Chain | Residue |
| B | ARG262 |
| B | GLY458 |
| B | VAL459 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | binding site for residue SO4 B 505 |
| Chain | Residue |
| A | TYR193 |
| B | THR315 |
| B | ASP316 |
| B | HIS317 |
| B | HOH666 |
| B | HOH713 |
| B | HOH729 |
| B | HOH736 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 B 506 |
| Chain | Residue |
| B | LEU237 |
| B | CYS238 |
| B | HIS253 |
| B | CYS254 |
| B | LYS401 |
| B | 7LX501 |
| B | HOH623 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 B 507 |
| Chain | Residue |
| A | HOH405 |
| B | SER453 |
| B | GLU454 |
| B | HOH652 |
| B | HOH720 |
| B | HOH776 |
| site_id | AC9 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 B 508 |
| Chain | Residue |
| B | MET366 |
| B | THR367 |
| B | ARG439 |
| B | HOH609 |
| B | HOH636 |
| B | HOH711 |
| B | HOH732 |
Functional Information from PROSITE/UniProt
| site_id | PS01186 |
| Number of Residues | 16 |
| Details | EGF_2 EGF-like domain signature 2. CrCheGYslladgvsC |
| Chain | Residue | Details |
| A | CYS172-CYS187 | |
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. VSAAHC |
| Chain | Residue | Details |
| B | VAL249-CYS254 | |
| site_id | PS00135 |
| Number of Residues | 12 |
| Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. DSckGDSGGPHA |
| Chain | Residue | Details |
| B | ASP398-ALA409 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | ACT_SITE: Charge relay system => ECO:0000250 |
| Chain | Residue | Details |
| B | HIS253 | |
| B | ASP302 | |
| B | SER404 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000250 |
| Chain | Residue | Details |
| B | ASP398 | |
| Chain | Residue | Details |
| B | ASN382 | |
