5O0W

Crystal structure of the complex between Nb474 and Trypanosoma congolense fructose-1,6-bisphosphate aldolase

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	Fructose-bisphosphate aldolase	polymer	387	42708.6	4	UniProt (G0UWE7) Pfam (PF00274) In PDB	Trypanosoma congolense (strain IL3000)
2	E, F, G, H	Nb474	polymer	143	15800.1	4		Vicugna pacos
3	A, B, C, D	GLYCEROL	non-polymer		92.1	6	Chemie (GOL)
4		water	water		18.0	516	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 372 (UniProt: G0UWE7)

PDB	External Database	Details
Glu 373	-	expression tag
Asn 374	-	expression tag
Leu 375	-	expression tag
Tyr 376	-	expression tag
Phe 377	-	expression tag
Gln 378	-	expression tag
Ser 379	-	expression tag
Gly 380	-	expression tag
Gly 381	-	expression tag
His 382	-	expression tag
His 383	-	expression tag
His 384	-	expression tag
His 385	-	expression tag
His 386	-	expression tag
His 387	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	234034.8
Non-Polymers*	Number of molecules	6
	Total formula weight	552.6
All*	Total formula weight	234587.4

*Water molecules are not included.