5O0W
Crystal structure of the complex between Nb474 and Trypanosoma congolense fructose-1,6-bisphosphate aldolase
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004332 | molecular_function | fructose-bisphosphate aldolase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006096 | biological_process | glycolytic process |
| A | 0016829 | molecular_function | lyase activity |
| A | 0030388 | biological_process | fructose 1,6-bisphosphate metabolic process |
| B | 0004332 | molecular_function | fructose-bisphosphate aldolase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0006096 | biological_process | glycolytic process |
| B | 0016829 | molecular_function | lyase activity |
| B | 0030388 | biological_process | fructose 1,6-bisphosphate metabolic process |
| C | 0004332 | molecular_function | fructose-bisphosphate aldolase activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0005829 | cellular_component | cytosol |
| C | 0006096 | biological_process | glycolytic process |
| C | 0016829 | molecular_function | lyase activity |
| C | 0030388 | biological_process | fructose 1,6-bisphosphate metabolic process |
| D | 0004332 | molecular_function | fructose-bisphosphate aldolase activity |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0005829 | cellular_component | cytosol |
| D | 0006096 | biological_process | glycolytic process |
| D | 0016829 | molecular_function | lyase activity |
| D | 0030388 | biological_process | fructose 1,6-bisphosphate metabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | binding site for residue GOL A 401 |
| Chain | Residue |
| A | ILE203 |
| A | ASN242 |
| A | MET243 |
| A | VAL245 |
| A | LEU281 |
| A | GLY283 |
| A | GLY284 |
| A | LEU285 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | binding site for residue GOL B 401 |
| Chain | Residue |
| B | ASN242 |
| B | MET243 |
| B | VAL245 |
| B | LEU281 |
| B | SER282 |
| B | GLY283 |
| B | GLY284 |
| B | HOH534 |
| B | ILE203 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue GOL C 401 |
| Chain | Residue |
| A | GLU179 |
| A | ARG229 |
| C | GLU179 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | binding site for residue GOL C 402 |
| Chain | Residue |
| C | ILE203 |
| C | ASN242 |
| C | MET243 |
| C | LEU281 |
| C | SER282 |
| C | GLY283 |
| C | GLY284 |
| site_id | AC5 |
| Number of Residues | 1 |
| Details | binding site for residue GOL D 401 |
| Chain | Residue |
| D | GLU179 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | binding site for residue GOL D 402 |
| Chain | Residue |
| D | ILE203 |
| D | ASN242 |
| D | MET243 |
| D | VAL245 |
| D | LEU281 |
| D | SER282 |
| D | GLY284 |
| D | LEU285 |
Functional Information from PROSITE/UniProt
| site_id | PS00158 |
| Number of Residues | 11 |
| Details | ALDOLASE_CLASS_I Fructose-bisphosphate aldolase class-I active site. VvWEGcLLKPN |
| Chain | Residue | Details |
| A | VAL232-ASN242 |
