Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

5MJ3

INTERLEUKIN-23 COMPLEX WITH AN ANTAGONISTIC ALPHABODY, CRYSTAL FORM 1

Replaces:  4OE8
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1AInterleukin-12 subunit betapolymer30634739.91UniProt (P29460)
Pfam (PF10420)
In PDB
Homo sapiens (Human)IL-12B,Cytotoxic lymphocyte maturation factor 40 kDa subunit,CLMF p40,IL-12 subunit p40,NK cell stimulatory factor chain 2,NKSF2
2BInterleukin-23 subunit alphapolymer17919812.31UniProt (Q9NPF7)
Pfam (PF16649)
In PDB
Homo sapiens (Human)IL-23-A,Interleukin-23 subunit p19,IL-23p19
3CALPHABODY MA12polymer11811945.61synthetic construct
4Dalpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched910.81In PDB
GlyTouCan (G22768VO)
5ATRIETHYLENE GLYCOLnon-polymer150.22Chemie (PGE)
6ATETRAETHYLENE GLYCOLnon-polymer194.21Chemie (PG4)
7ASODIUM IONnon-polymer23.02Chemie (NA)
8waterwater18.0417Chemie (HOH)
Sequence modifications
B: 20 - 189 (UniProt: Q9NPF7)
PDBExternal DatabaseDetails
Gly 190-expression tag
Thr 191-expression tag
Lys 192-expression tag
His 193-expression tag
His 194-expression tag
His 195-expression tag
His 196-expression tag
His 197-expression tag
His 198-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight66497.9
BranchedNumber of molecules1
Total formula weight910.8
Non-Polymers*Number of molecules5
Total formula weight540.6
All*Total formula weight67949.2
*Water molecules are not included.

219140

PDB entries from 2024-05-01

PDB statisticsPDBj update infoContact PDBjnumon