5LYO
Crystal structure of the zymogen matriptase catalytic domain
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C | Suppressor of tumorigenicity 14 protein | polymer | 265 | 29132.7 | 3 | UniProt (Q9Y5Y6) Pfam (PF00089) In PDB | Homo sapiens (Human) | Matriptase,Membrane-type serine protease 1,MT-SP1,Prostamin,Serine protease 14,Serine protease TADG-15,Tumor-associated differentially-expressed gene 15 protein |
2 | A, B, C | SULFATE ION | non-polymer | 96.1 | 21 | Chemie (SO4) | |||
3 | water | water | 18.0 | 167 | Chemie (HOH) |
Sequence modifications
A, B, C: 604 - 855 (UniProt: Q9Y5Y6)
PDB | External Database | Details |
---|---|---|
Ser 591 | - | expression tag |
Met 592 | - | expression tag |
Asn 593 | - | expression tag |
Ser 594 | - | expression tag |
His 595 | - | expression tag |
His 596 | - | expression tag |
His 597 | - | expression tag |
His 598 | - | expression tag |
His 599 | - | expression tag |
His 600 | - | expression tag |
Gly 601 | - | expression tag |
Thr 602 | - | expression tag |
Ala 603 | - | expression tag |
Ala 614 | Arg 614 | engineered mutation |
Gln 772 | Asn 772 | engineered mutation |
Ala 805 | Ser 805 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 87398.2 | |
Non-Polymers* | Number of molecules | 21 |
Total formula weight | 2017.3 | |
All* | Total formula weight | 89415.5 |