Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004252 | molecular_function | serine-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| B | 0004252 | molecular_function | serine-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
| C | 0004252 | molecular_function | serine-type endopeptidase activity |
| C | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 901 |
| Chain | Residue |
| A | HIS656 |
| A | ALA805 |
| A | TRP826 |
| A | GLY827 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 A 902 |
| Chain | Residue |
| A | ARG684 |
| A | HIS633 |
| A | LEU635 |
| A | GLY636 |
| A | GLN637 |
| A | GLY638 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 903 |
| Chain | Residue |
| A | ASP734 |
| A | HIS737 |
| A | PHE819 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 A 904 |
| Chain | Residue |
| A | ARG611 |
| A | GLN612 |
| A | ARG833 |
| B | GLN832 |
| B | ASN834 |
| B | LYS835 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 905 |
| Chain | Residue |
| A | HIS752 |
| A | THR758 |
| C | GLN772 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 A 906 |
| Chain | Residue |
| A | GLU691 |
| A | ARG692 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 A 907 |
| Chain | Residue |
| A | VAL770 |
| A | HOH1002 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 B 901 |
| Chain | Residue |
| B | HIS656 |
| B | ALA805 |
| B | TRP826 |
| B | GLY827 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 B 902 |
| Chain | Residue |
| B | HIS633 |
| B | GLY636 |
| B | GLN637 |
| B | GLY638 |
| B | ARG684 |
| site_id | AD1 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 B 903 |
| Chain | Residue |
| B | GLN690 |
| B | GLU691 |
| B | ARG692 |
| site_id | AD2 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 B 904 |
| Chain | Residue |
| B | ARG833 |
| B | ASN834 |
| B | HOH1004 |
| B | HOH1024 |
| site_id | AD3 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 B 905 |
| Chain | Residue |
| A | GLN772 |
| B | HIS752 |
| B | THR758 |
| B | HOH1013 |
| site_id | AD4 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 C 901 |
| Chain | Residue |
| C | HIS656 |
| C | ALA805 |
| C | TRP826 |
| C | GLY827 |
| site_id | AD5 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 C 902 |
| Chain | Residue |
| A | PHE706 |
| C | PRO648 |
| C | ALA721 |
| C | GLU722 |
| C | TYR723 |
| site_id | AD6 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 C 903 |
| Chain | Residue |
| C | PRO733 |
| C | ASP734 |
| C | HIS737 |
| site_id | AD7 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 C 904 |
| Chain | Residue |
| B | GLN772 |
| C | HIS752 |
| C | THR758 |
| C | HOH1008 |
| site_id | AD8 |
| Number of Residues | 8 |
| Details | binding site for residue SO4 C 905 |
| Chain | Residue |
| A | ARG833 |
| A | HOH1006 |
| A | HOH1024 |
| A | HOH1029 |
| A | HOH1047 |
| A | HOH1054 |
| B | ARG833 |
| C | ARG833 |
| site_id | AD9 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 C 906 |
| Chain | Residue |
| C | THR610 |
| C | ARG833 |
| C | ASN834 |
| site_id | AE1 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 C 907 |
| Chain | Residue |
| C | ARG607 |
| C | PHE609 |
| C | GLU625 |
| C | TRP626 |
| site_id | AE2 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 C 908 |
| Chain | Residue |
| C | VAL689 |
| C | GLN690 |
| C | GLU691 |
| C | ARG692 |
| C | GLU722 |
| site_id | AE3 |
| Number of Residues | 1 |
| Details | binding site for residue SO4 C 909 |
Functional Information from PROSITE/UniProt
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. VSAAHC |
| Chain | Residue | Details |
| A | VAL652-CYS657 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 9 |
| Details | ACT_SITE: Charge relay system |
| Chain | Residue | Details |
| A | HIS656 | |
| A | ASP711 | |
| A | ALA805 | |
| B | HIS656 | |
| B | ASP711 | |
| B | ALA805 | |
| C | HIS656 | |
| C | ASP711 | |
| C | ALA805 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | GLN772 | |
| B | GLN772 | |
| C | GLN772 | |
