5LHB
POLYADPRIBOSYL GLYCOSIDASE IN COMPLEX WITH PDD00017262
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Poly(ADP-ribose) glycohydrolase | polymer | 531 | 61096.5 | 1 | UniProt (Q86W56) Pfam (PF20811) Pfam (PF05028) In PDB | Homo sapiens (Human) | |
| 2 | A | 1-(cyclopropylmethyl)-6-[[(1-methylcyclopropyl)amino]-bis(oxidanyl)-$l^{4}-sulfanyl]-3-[(2-methyl-1,3-thiazol-5-yl)methyl]quinazoline-2,4-dione | non-polymer | 462.6 | 1 | Chemie (6WJ) | |||
| 3 | A | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 4 | A | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 3 | Chemie (DMS) | |||
| 5 | water | water | 18.0 | 300 | Chemie (HOH) |
Sequence modifications
A: 448 - 976 (UniProt: Q86W56)
| PDB | External Database | Details |
|---|---|---|
| Gly 446 | - | expression tag |
| Ser 447 | - | expression tag |
| Ala 616 | Lys 508 | engineered mutation |
| Ala 617 | Gln 509 | engineered mutation |
| Ala 618 | Lys 510 | engineered mutation |
| 6wk 681 | Cys 573 | modified residue |
| Ala 688 | Glu 580 | engineered mutation |
| Ala 689 | Lys 581 | engineered mutation |
| Ala 690 | Lys 582 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 61096.5 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 985.2 | |
| All* | Total formula weight | 62081.7 |
