5JNW
Crystal structure of bovine low molecular weight protein tyrosine phosphatase (LMPTP) mutant (W49Y N50E) complexed with vanadate and uncompetitive inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Low molecular weight phosphotyrosine protein phosphatase | polymer | 159 | 18082.4 | 1 | UniProt (P11064) Pfam (PF01451) In PDB | Bos taurus (Bovine) | protein tyrosine phosphatase, hydrolase, LMW-PTP, LMPTP |
| 2 | A | VANADATE ION | non-polymer | 114.9 | 1 | Chemie (VO4) | |||
| 3 | A | 2-(4-{[3-(piperidin-1-yl)propyl]amino}quinolin-2-yl)benzonitrile | non-polymer | 370.5 | 1 | Chemie (6LJ) | |||
| 4 | water | water | 18.0 | 153 | Chemie (HOH) |
Sequence modifications
A: 1 - 157 (UniProt: P11064)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Tyr 49 | Trp 50 | conflict |
| Glu 50 | Asn 51 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 18082.4 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 485.4 | |
| All* | Total formula weight | 18567.9 |
